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Black skin cancer: immunotherapy for skin cancer recommended

Black skin cancer: immunotherapy for skin cancer recommended


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Updated guidelines for the treatment of black skin cancer

The German Cancer Society and other specialist societies announce that changes to the melanoma guideline have been published. There are new recommendations, particularly in the treatment of black skin cancer.

Several specialist societies, including the German Dermatological Society (DDG) and the Dermatological Oncology Working Group (ADO) of the German Cancer Society (DKG), have updated the S-3 guideline "Diagnostics, therapy and aftercare of melanoma", which was published in 2018. Here are the most important changes.

New insights added

Professor Dr. Thomas Eigenler is one of the guideline coordinators who contributed to the revision. "A lot has happened in the field of adjuvant therapy due to newly approved therapeutic agents and an improved study situation, which is why we have updated the corresponding chapter in the guidelines," explains the professor.

More immunotherapy for skin cancer is recommended

There are some changes in the recommendations, particularly in the treatment of advanced skin cancer. For example, those who suffer from advanced black skin cancer are more likely to receive immune treatment and targeted therapy.

High relapse rate for metastases

This mainly affects patients who have metastases in the lymph nodes and skin (stage III) or distant metastases (stage IV). It was shown that there was a high relapse rate after the surgical removal of the metastases. "Among other things, a new recommendation is that sufferers in stage III and IV should be offered adjuvant therapy with an anti-PD1 antibody or with targeted therapy in stage III without evidence of metastases," said Eigenler. This could stop the disease from progressing.

Black skin cancer is common

As the experts from the German Cancer Society report, skin malignant melanoma is one of the five most common tumor diseases in Germany. In 2014, around 21,200 people contracted the malignant skin cancer. Around 3,000 people died from it.

Black skin cancer is the most dangerous skin tumor

As statistics from the Robert Koch Institute show, there has been a steady increase in new cases since the 1970s. Since then, the number of illnesses has more than quintupled. Malignant melanoma is particularly dangerous among skin cancers because it has the highest metastatic rate. Among all skin tumors, black skin cancer is responsible for around 90 percent of all deaths.

Fashion trend takes revenge

At the 50th DDG conference, experts drew attention to the rising number of skin cancer in Germany. According to the experts, a fashion trend from the 70s and 80s is particularly responsible for the increasing numbers: the massive and unprotected tanning of the skin. More information can be found in the article: Skin cancer wave: fashion trends of the 70s and 80s are now taking revenge. (vb)

Author and source information

This text corresponds to the requirements of the medical literature, medical guidelines and current studies and has been checked by medical doctors.

Graduate editor (FH) Volker Blasek

Swell:

  • Guideline program oncology: S3 guideline diagnostics, therapy and aftercare of melanoma, version 3.2, status: October 2019, leitlinienprogramm-onkologie.de
  • German Dermatological Society (DDG): Black skin cancer: New guideline recommendations for patients at an advanced stage (accessed: December 5, 2019), derma.de



Video: The 4 Stages of Melanoma: The Deadliest Form of Skin Cancer - Mayo Clinic (October 2022).