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Probiotic agent for the treatment of colic
A recent study showed that drops containing a certain probiotic strain reduce infant colic and have positive effects on sleep and bowel movements.
The current study by the University of Naples Federico II has now found that colic in young children can be treated with probiotic drops. The results of the study were published in the English-language journal "Alimentary Pharmacology & Therapeutics".
Which probiotic strain led to the improvements?
When children with colic drop with the probiotic strain Bifidobacterium animalis subsp. lactis BB-12 according to the crying and crying, improves sleep and also has positive effects on the child's bowel movements.
Positive effects of the drops
If the drug was taken once a day for 28 days, crying and crying decreased by more than half in 80 percent of the children examined. This also had a positive effect on sleep duration, stool frequency and stool consistency. In contrast, when the infants received a placebo, the success rate was only 32.5 percent.
Children's colic also affects parents
The so-called infant colic is a very common gastrointestinal disease that affects up to 25 percent of infants in the first three months of life. The disease is a heavy burden for infants and their families. For example, infant colic can contribute to maternal postpartum depression, frustration, shorter breastfeeding, multiple visits to the doctor, and long-term undesirable results such as allergies, behavior changes, and sleep disorders.
The positive effects are due to butyrate
The effect found in the study was associated with positive modulation of the gut microbiome. There has been an increased bacterial production of butyrate, a short chain fatty acid, which is able to positively influence intestinal transit time, pain perception, the intestinal axis and inflammation.
Results do not apply to other probiotic strains
The study provides evidence of the important role of the gut microbiota as a target for intervention against child colic. The study examined a certain already well-characterized probiotic strain, which means that the results cannot be extended to other probiotic strains, the researchers report. (as)
Author and source information
This text corresponds to the specifications of the medical literature, medical guidelines and current studies and has been checked by medical doctors.
- Rita Nocerino, Francesca De Filippis, Gaetano Cecere, Antonio Marino, Maria Micillo et al .: The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB ‐ 12® in infant colic: A randomized, double blind, placebo ‐ controlled trial, in Alimentary Pharmacology & Therapeutics (query: 04.12.2019), Alimentary Pharmacology & Therapeutics